The rats feeding on high-cholesterol diet expressed hypercholesterolemia and fatty liver and showed impaired hepatic function. In the Rice Kefiran-fed groups, the activity of aminotransferases (GOT, GPT) was significantly decreased in both the 1.5% and 3.0% groups. This result suggests that Rice Kefiran has an improvement action on the hepatic function.
■Improvement of hepatic function by the intake of Rice Kefiran in rats feeding
on high-cholesterol diet
|
Control group
|
1.5% Rice Kefiran
group
|
3.0% Rice Kefiran
group
|
Liver weight (g)
|
19.3± 0.7
|
20.0± 0.5
|
19.9± 0.8
|
Total cholesterol
(μmol/g)
|
725.5±43.9
|
841.8±63.8
|
868.2±56.1
|
Triglyceride
(μmol/g)
|
79.4± 4.7
|
87.4± 6.9
|
77.7±10.0 |
Phospholipid
(μmol/g)
|
106.1± 3.1ab
|
112.4± 1.7a
|
99.2± 4.6b
|
GOT(U/L)
|
137.0±13.6a
|
92.6± 7.9b
|
78.5± 6.8b
|
GPT(U/L)
|
36.5± 1.2a
|
31.2± 1.7b
|
18.9± 3.5c
|
Mean ± standard error (n=6). a,bValues with different superscriptions are significantly different (p < 0.05).
|